Cryoprotection–lyophilization and physical stabilization of rifampicin-loaded flower-like polymeric micelles
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چکیده
منابع مشابه
Cryoprotection-lyophilization and physical stabilization of rifampicin-loaded flower-like polymeric micelles.
Rifampicin-loaded poly(ε-caprolactone)-b-poly(ethylene glycol)-poly(ε-caprolactone) flower-like polymeric micelles display low aqueous physical stability over time and undergo substantial secondary aggregation. To improve their physical stability, the lyoprotection-lyophilization process was thoroughly characterized. The preliminary cryoprotectant performance of mono- and disaccharides (e.g. ma...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2011
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2011.0414